No. As of September 1, 2026, Rockstar has not confirmed any sex scenes, sexual mechanics, or adult content beyond what you would expect from a mature-rated title. Neither Trailer 1 (December 4, 2023), Trailer 2 (May 6, 2025), nor the 26-minute Extended Look (August 27, 2026) shows anything of the sort. The Extended Look focuses on open-world systems, gunplay, and the dual-protagonist setup with Lucia and Jason.
GTA V had brief, non-interactive sex scenes and a strip club, so some players expect GTA 6 to include similar elements. That is a reasonable guess, but it remains unconfirmed. Rockstar has not mentioned sexuality, romance, or any adult interactions in any official material. The ESRB rating for GTA 6 has not been published yet, so we cannot point to official content descriptors.
If you are asking about interactive sex, as in player-controlled encounters, no GTA game has ever had that. GTA V and GTA Online only had scripted scenes. There is no evidence GTA 6 changes that. Treat any claim about sex mechanics in GTA 6 as a rumour until Rockstar says otherwise. The safest answer for now: do not expect it.