No. Rockstar has not confirmed cross-play for Grand Theft Auto VI, and nothing in the official announcements or store listings mentions it. The game launches November 19, 2026 on PlayStation 5 and Xbox Series X|S as a single-player experience, with no online mode announced.
Cross-play usually matters for multiplayer, and GTA 6 ships without one. Rockstar has not detailed any online component, so there is nothing to enable cross-play for at launch. If a separate online mode arrives later, cross-play support would be a separate decision, and no such plan has been reported.
Historical context: GTA Online on last-gen consoles never supported cross-play between PlayStation and Xbox, even years after release. That suggests Rockstar is not inclined to build it, but it does not rule it out for a future GTA 6 online mode.
What you can expect at launch: single-player only, no cross-play, no cross-save between PS5 and Xbox, and no PC version announced. Treat any claim of cross-play as speculation until Rockstar says otherwise.