No, there is no gameplay element or story beat in GTA 6 that involves a second coming. The game is set in modern-day Leonida, and Rockstar has confirmed no supernatural or religious end-times narrative. The only return date that matters to players is the November 19, 2026 launch on PS5 and Xbox Series X|S.
What the game actually includes
Confirmed content from the August 27, 2026 Extended Look and store listings: a single-player campaign following Lucia and Jason, the Vice City metro area, and the Vintage Vice City Pack pre-order bonus. No DLC roadmap, no online mode, no post-launch story content has been announced.
If you are asking about a real-world religious event, that falls outside game coverage. But if you are asking whether GTA 6 will feature any messianic characters or apocalyptic plotlines, nothing in official material suggests it. The tone is grounded crime drama, not prophecy.
For reference, GTA 5 took 19 months to reach PC after consoles. GTA 6 has no PC version announced at all, so the waiting game is already longer for that platform. Jesus, as far as we know, has no scheduled patch.